Occupational Toxicity an Unnoticed Health Risk: A Review

Authors

  • Ms. Triptikana Chakraborty
  • Mr. Khurshid Alam Lasker
  • Dr. Titlee Majumder
  • Mr. Kazi Md. Refayetullah
  • Dr. Subrata Ghosh

DOI:

https://doi.org/10.53555/ejac.v20i1.1141

Keywords:

OSHA, NIOSH, Occupational Toxicology, respiratory disorders, workplace health

Abstract

Occupational toxicity is a branch of science that focuses upon the study and assessment of harmful chemicals or toxic substances, captivating the workplace. This field is critical for ensuring the health and safety of workers by identifying, evaluating, and controlling exposures to hazardous substances. Occupational toxicologists identify chemicals, dusts, fumes, gases, and physical agents (like radiation) that workers may be exposed to during their jobs and also identify their routes of exposure. The dose of the toxic substances and the frequency of exposure lead to many acute and chronic clinical conditions for workers. Developing safety guidelines preventive measures, such as permissible exposure limits (PELs) and threshold limit values (TLVs), workers can be protected in the work zone. Toxic substance induced occupational diseases, such as respiratory disorders, skin conditions, neurological effects, and cancers have become common for now these days. Ergonomics and occupational health management aim to identify and prevent those health risks. Recommendation of PPE, gloves, masks, and covered clothing, reduce the chances of toxicity. There are many standardise protocols declared by OSHA, NIOSH have been followed by industries as well as organizations for taking best protection. By understanding the risks associated with workplace, occupational toxicologists or health experts help in designing safer industrial processes, implementing effective control measures, and developing policies that protect workers from harmful effects, thereby reducing the incidence of occupational diseases by improving overall workplace health.

Author Biographies

  • Ms. Triptikana Chakraborty

    Research Scholar, Hooghly Mohsin College, The University of Burdwan, Chinsurah, Hooghly. 

  • Mr. Khurshid Alam Lasker

    Assistant Professor, Department of Allied Health Sciences, Institute of Leadership Entrepreneurship & Development, Kolkata

     

     

     

  • Dr. Titlee Majumder

    Assistant Professor, Grade II, Department of Medical Laboratory Technology, Techno India University, 

     

  • Mr. Kazi Md. Refayetullah

    Assistant Professor, Kolkata, Department of Allied Health Sciences, Institute of Leadership Entrepreneurship & Development, Kolkata

     

  • Dr. Subrata Ghosh

    Associate Professor, Department of Physiology, Hooghly Mohsin College, The University of Burdwan, Chinsurah Hooghly. 

References

Landrigan, P. J., & Baker, D. B. (1991). The recognition and control of occupational disease. Jama, 266(5), 676-680.

Perlman, D. M., & Maier, L. A. (2019). Occupational lung disease. Medical clinics, 103(3), 535-548.

Xiaoyou Tang, Tingyi Yang, Daojiang Yu, Hai Xiong, Shuyu Zhang, Current insights and future perspectives of ultraviolet radiation (UV) exposure: Friends and foes to the skin and beyond the skin, Environment International, Volume 185, 2024, 108535, ISSN 0160-4120, https://doi.org/10.1016/j.envint.2024.108535.

Fadi Ibrahim, Tariq Khan, Bacterial Skin Infections, December 2015, Primary Care Clinics in Office Practice 42(4):485-499, DOI:10.1016/j.pop.2015.08.001

Scammell, M. K., Sennett, C. M., Petropoulos, Z. E., Kamal, J., & Kaufman, J. S. (2019, May). Environmental and occupational exposures in kidney disease. In Seminars in nephrology (Vol. 39, No. 3, pp. 230-243). WB Saunders.

Lim, J. W., & Koh, D. (2014). Chemical agents that cause occupational diseases. The Wiley Blackwell Encyclopedia of Health, Illness, Behavior, and Society.

Nguyen VK, Colacino J, Patel CJ, Sartor M, Jolliet O. Identification of occupations susceptible to high exposure and risk associated with multiple toxicants in an observational study: National Health and Nutrition Examination Survey 1999-2014. Exposome. 2022 Jun 25;2(1):osac004. doi: 10.1093/exposome/osac004. PMID: 35832257; PMCID: PMC9266352.

Coates, T., & Clark, A. R. L. (1990). Occupational diseases. In Safety At Work (pp. 344-376). Butterworth-Heinemann.

Newman, L. S. (1995). Occupational illness. New England Journal of Medicine, 333(17), 1128-1134.

Riva, M. A., Lafranconi, A., D’orso, M. I., & Cesana, G. (2012). Lead poisoning: historical aspects of a paradigmatic “occupational and environmental disease”. Safety and health at work, 3(1), 11-16.

Eklund M, Parsonage-Harrison J, Argentzell E. Occupation- and lifestyle-based mental health interventions – A hallmark for the occupational therapy profession? British Journal of Occupational Therapy. 2024;87(7):395-397.

Cahill SM, Egan BE, Seber J. Activity- and Occupation-Based Interventions to Support Mental Health, Positive Behavior, and Social Participation for Children and Youth: A Systematic Review. Am J Occup Ther. 2020 Mar/Apr;74(2):7402180020p1-7402180020p28. doi: 10.5014/ajot.2020.038687. PMID: 32204773.

Rim, K. T. (2021). Exposure of chemical mixtures at work and their application to the prevention of occupational disease. Toxicology and Environmental Health Sciences, 13, 91-99.

Baveye, P., & Laba, M. (2008). Aggregation and toxicology of titanium dioxide nanoparticles. Environmental Health Perspectives, 116(4), A152-A152.

Burnase, N., Jaiswal, S., &Barapatre, A. (2022). Metal Toxicity in Humans Associated with Their Occupational Exposures Due to Mining. In Medical Geology in Mining: Health Hazards Due to Metal Toxicity (pp. 127-186). Cham: Springer International Publishing.

Salleh, N., Yhaya, M. F., Ghafar, N. A., Muslim, N. Z. M., & Hamzah, N. A. (2021). Occupational-related Disease to the Toxicity of Benzene Derivatives Exposure among Working Populations: A Review. Malaysian Journal of Medicine & Health Sciences, 17.

Ross, M. H., & Murray, J. (2004). Occupational respiratory disease in mining. Occupational medicine, 54(5), 304-310.

E.V. Sargent, B.D. Naumann, C.S. Schwartz,3.06 - Occupational Toxicology Testing, Editor(s): Charlene A. McQueen, Comprehensive Toxicology (Second Edition), Elsevier,2010, Pages 65-85, ISBN 9780080468846, https://doi.org/10.1016/B978-0-08-046884-6.00310-9.

Manzo, L., & Costa, L. G. (2020). Manifestations of neurotoxicity in occupational diseases. In Occupational Neurotoxicology (pp. 1-20). CRC Press.

Manzo, L., & Costa, L. G. (2020). Manifestations of neurotoxicity in occupational diseases. In Occupational Neurotoxicology (pp. 1-20). CRC Press.

Michaelis, S., Burdon, J., Howard, C. V., & World Health Organization. (2017). Aerotoxic syndrome: a new occupational disease?. Public Health Panorama, 3(02), 198-211.

Tiller, J. R., Schilling, R. S., & Morris, J. N. (1968). Occupational toxic factor in mortality from coronary heart disease. Br med j, 4(5628), 407-411.

Kaur, K., & Kaur, R. (2018). Occupational pesticide exposure, impaired DNA repair, and diseases. Indian journal of occupational and environmental medicine, 22(2), 74-81.

Nishida, C., &Yatera, K. (2022). The impact of ambient environmental and occupational pollution on respiratory diseases. International journal of environmental research and public health, 19(5), 2788.

Rim, K. T. (2023). Occupational exposure to mixtures and toxic pathways prediction for workers’ health. Molecular & Cellular Toxicology, 19(4), 775-788.

Markowitz, S. B., Fischer, E., Fahs, M. C., Shapiro, J., & Landrigan, P. J. (1989). Occupational disease in New York State: a comprehensive examination. American Journal of Industrial Medicine, 16(4), 417-435.

Oliver, L. C., & Zarnke, A. M. (2021). Sarcoidosis: an occupational disease?. Chest, 160(4), 1360-1367.

Gangemi, S., Miozzi, E., Teodoro, M., Briguglio, G., De Luca, A., Alibrando, C., ... & Libra, M. (2016). Occupational exposure to pesticides as a possible risk factor for the development of chronic diseases in humans. Molecular medicine reports, 14(5), 4475-4488.

Ekor, M., &Odewabi, A. O. (2014). Occupational exposure to municipal solid wastes and development of toxic neuropathies: Possible role of nutrient supplementation, complementary and alternative medicines in chemoprevention. Chinese journal of integrative medicine, 20, 643-653.

Gracia, R. C., & Snodgrass, W. R. (2007). Lead toxicity and chelation therapy. American journal of health-system pharmacy, 64(1), 45-53.

Flack, S., & Nylander-French, L. A. (2012). Occupational chemicals: metabolism, toxicity, and mode of action. Progress in molecular biology and translational science, 112, 163-207.

"Update of occupational lung disease." Journal of occupational health 61, no. 1 (2019): 10-18.

McCunney, R. J., Yong, M., Warheit, D. B., & Morfeld, P. (2022). Occupational exposure to poorly soluble low toxicity particles and cardiac disease: a look at carbon black and titanium dioxide. Frontiers in Public Health, 10, 909136.

Linz, D. H., Barker, A. F., Morton, W. E., &deGarmo, P. L. (1985). Occupational toxic inhalations. Advanced Emergency Nursing Journal, 7(1), 21-33.

Alshamrani, M. (2022). IoT and artificial intelligence implementations for remote healthcare monitoring systems: A survey. Journal of King Saud University-Computer and Information Sciences, 34(8), 4687-4701.

Kishor, A., & Chakraborty, C. (2022). Artificial intelligence and internet of things based healthcare 4.0 monitoring system. Wireless personal communications, 127(2), 1615-1631.

Greco, L., Percannella, G., Ritrovato, P., Tortorella, F., & Vento, M. (2020). Trends in IoT based solutions for health care: Moving AI to the edge. Pattern recognition letters, 135, 346-353.

Juyal, S., Sharma, S., & Shukla, A. S. (2021). Smart skin health monitoring using AI-enabled cloud-based IoT. Materials Today: Proceedings, 46, 10539-10545.

Kar, N. (2003). Mental ill health in workers: observations from a few Indian populations. Occupational and environmental medicine, 60(3), 225-225.

Vijayakumar, C., Vignesha, T., Murugesan, A., & Bavana, N. (2015). Effect of Erroneous In Ergonomics and Its Remedies to Workers in Industries‒A Literature Survey. International Journal on Recent and Innovation Trends in Computing and Communication, 3(1), 368-377.

Dhole, R., Patil, D., & Kapoor, A. (2021). Impact of workstation exercise and ergonomic exercise on nursing population–A randomized clinical trial research protocol. Indian Journal of Forensic Medicine & Toxicology, 15(1), 622-627.

Reddy, D. S. (1973). GLIMPSES OF THE ART OF MEDICINE AND MEDICAL AND IN ANCIENT SOUTH INDIA. Journal of Indian Medical Heritage, 3(3), 135-139.

Hanumaiah, V., & Manjunath, H. (2018). Study of knowledge, attitude and practice of self medication among health care workers at MC gann teaching district hospital of Shivamogga, India. Int J Basic Clin Pharmacol, 7(6), 1174-1181.

Ramanna, M. (2002). Western medicine and public health in colonial Bombay, 1845-1895 (Vol. 4). Orient Blackswan.

Vanishree, N., Jeswin, J., & Chaithra, V. (2013). A Study to Assess the Musculoskeletal Pain among Dental Postgraduate Students in Bangalore City, India. Indian Journal of Contemporary Dentistry, 1(1), 29.

Downloads

Published

19-02-2025

Issue

Section

Articles