Determination of diethylamine and triethylamine quantitatively using GC-headspace chromatography
Keywords:
GC-HS, Diethylamine (DEA), Triethylamine (TEA), Dimethylsulfoxide (DMSO)Abstract
A Gas chromatographic-Head space (GC-HS) method was developed and validated for the
determination of Diethylamine and Triethylamine. They were found well separated on the DB-624,
30m x 0.530 mm I.D. X 3 µ column with carrier gas nitrogen having pressure of 2.5 psi (Pound per
square inch). Injector temperature was kept at 220°C and detector temperature was kept at 250°C.
Detection was performed flame ionisation detector (FID). The method was validated for Specificity,
LOD, LOQ, Linearity, Precision and Accuracy as per ICH guidelines [1, 2]. The method was found to
be reliable for its intended purpose