Synthesis, Spectral Identification, Thermal And Anticancer Studies of Co(III),Cu(II) And Au(III) Complexes With New ThiazolylAzo Ligand

Abstract

The complexes azo ligand 2-[2--(5-Methyl thiazolyl)azo]-4,6 –dimethyl phenol
(MeTADMeP) with Co(III),Cu(II) And Au(III) Complexes were prepared. The azo ligand and
its complexes had been characterized by FT-IR, 1H- NMR,13C- NMR, UV-Vis measurments,
Mass spectrum, magnetic susceptibility, elemental analyses (C.H.N.S), molar conductance,
(TGA), FESEM and X-ray diffraction studies(XRD). This work also included the biological
activity testing of azo dye ligand and their complexes against the sensitive organisms
Escherichia coli (gram negative), streptococcus (gram positive) as antibacterial and
Aspergillus Niger and Penicillium as antifungal, azo dye ligand and Au(III) Complex show
cytotoxis action against human Bladder Cancer cell line (UBC40).