Synthesis, Spectral Identification, Thermal and Anticancer Studies of Co(III),Cu(II) and Au(III) Complexes With New ThiazolylAzo Ligand

Abstract

The complexes azo ligand 2-[2--(5-Methyl thiazolyl)azo]-4,6 –dimethyl phenol
(MeTADMeP) with Co(III),Cu(II) And Au(III) Complexes were prepared. The azo ligand
and its complexes had been characterized by FT-IR, 1H- NMR,13C- NMR, UV-Vis
measurments, Mass spectrum, magnetic susceptibility, elemental analyses (C.H.N.S), molar
conductance, (TGA), FESEM and X-ray diffraction studies(XRD). This work also included
the biological activity testing of azo dye ligand and their complexes against the sensitive
organisms Escherichia coli (gram negative), streptococcus (gram positive) as antibacterial
and Aspergillus Niger and Penicillium as antifungal, azo dye ligand and Au(III) Complex
show cytotoxis action against human Bladder Cancer cell line (UBC40).