Evaluation Of Clinical Profile And Outcomes Of Tubercular Pleural Effusion Based On Its Biochemical And Cytological Findings.
Keywords:
Tuberculosis, Pleural Effusion, Biomarker, PleurocentesisAbstract
Background:
Tubercular pleural effusion (TPE) is a common manifestation of extrapulmonary tuberculosis, presenting significant diagnostic and therapeutic challenges. The purpose of this study was to evaluate the clinical profile and outcomes of patients with TPE, focusing on the biochemical and cytological characteristics of pleural fluid.
Method:
This cross-sectional study was conducted in the Department of General Medicine at a tertiary care center in Ballari. We enrolled a total of 110 patients based on predetermined inclusion and exclusion criteria. A pre-designed, semi-structured questionnaire was developed and underwent pilot testing to collect socio-demographic data for all participants. Subsequently, the clinical profile and outcomes of TPE were evaluated based on biochemical and cytological investigations.
Results:
In the present study, 110 consecutive patients with pleural effusions were enrolled from February 2020 to July 2020. Among the selected participants, 74 were males and 36 were female patients, with a mean age of 41.6±15.74 years. The symptoms such as cough were most common (70.9%), followed by fever (60%) and chest pain (41.9%). Breathlessness and sputum occurred in 23.6% and 12.7% of cases, respectively. For LN ratio and etiology, 71.8% of cases had an LN ratio >75%, with notable prevalence in E1 and E3.
Conclusion:
The present study highlighted that, the integration of routine laboratory investigations is crucial for the effective management of tubercular pleural effusion, leading to improved patient outcomes. Early diagnosis and comprehensive treatment remain essential for reducing morbidity and ensuring better recovery.
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