Study Of General And Histopathological Characteristics Of Sweat Gland Adnexal Skin Tumors-7 Year Study
Keywords:
tumours, skin, adnexa,studyAbstract
Background ; The clinical presentation, biological behavior and histological pattern of skin tumors vary widely . 1 The histopathology of tumors involving follicular, sebaceous, and apocrine epithelium is sometimes difficult to interpret .2 Difficulties arise from the diversity and complexity of histological, ultrastructural and histochemical studies, complex nomenclature, multiple classifications and disagreements in the histogenesis of some entities, and the relative rarity of these tumors. 3
This study was a retrospective and prospective study between September 2004 and September 2011. Total 18 sweat gland tumours (benign-16 malignant -2 ) obtained out of 133 skin tumours in and around solapur region . necessary general and special stainsdone with clinicopathological correlation .
RESULTS AND OBSERVATIONS: In the present study benign adnexal tumours formed the majority (82.8%).
There were 16 patients with sweat gland differentiation accounting for 55.2% of the benign adnexal tumours.
In the present study benign tumours formed the majority (82.8%).
Among the benign tumours the occurrence of sweat gland tumours (55.1%) was highest followed by hair follicle tumours (44.8%)
DISCUSSION; The occurrence of Chondroid syringoma and eccrine poroma (31.2%) was equal in the present study followed by spiradenoma (18.9%) ,hidradenoma (12.6 %) and apocrine hidrocystoma(6.3%).
In the study by Solanki RL(4,11) et al hidradenoma (27.6%) was the most common followed by 23.4% each of chondroid syringoma and syringocystadenoma papilliferum.In the study by Nair SP 6et al syringoma (73.7%) was the most common tumour.In the study by Reddy 4 et al hidradenoma(67.4%) was the most common tumour.
References
Murphy GF, Sellheyer K and Mihm MC. The skin. In Robbins and Cotran Pathological basis of disease. 7th ed. Philadelphia : Saunders; 2008.p.1227-1271.
Koh D, Wang H, Lee J, Chia KS, Lee HP and Goh CL. Basal cell carcinoma, squamous cell carcinoma and melanoma of the skin: analysis of the Singapore Cancer Registry data 1968-97. British journal of Dermatology; 148:1161-1166.
LeBoit PE, Burg G, Weedon D and Sarasin A. Pathology and genetics of skin tumours. In World health organisation classification of tumours. IARC press. Lyon, 2006.p.9-164.
Reddy KM, Veliath AJ, Nagarajan S and Arora AL. A clinicapathological study of adnexal tumours of skin. Indian J Med Res 75, June 1982:882-889.
Amin SP and Shah BH. Syringoma- a case report with review of literature. Indian journal of Dermatology, Venereology and Leprology, vol39, No 3;1973:133-137
Reddy KM, Veliath AJ, Nagarajan S and Arora AL. A clinicapathological study of adnexal tumours of skin. Indian J Med Res 75, June 1982:882-889.
Hashimoto, K. and Lever, W.F. (1969) Histogenesis of Skin Appendage Tumors. Archives of Dermatological, 100, 356-369.
http://dx.doi.org/10.1001/archderm.1969.01610270098021.
Shapiro, P. E., & Kopf, A. W. (1991). Familial multiple desmoplastic trichoepitheliomas. Archives of dermatology, 127(1), 83–87.
Alsaad, K. O., Obaidat, N. A., & Ghazarian, D. (2007). Skin adnexal neoplasms--part 1: an approach to tumours of the pilosebaceous unit. Journal of clinical pathology, 60(2), 129–144. https://doi.org/10.1136/jcp.2006.040337.
Beck S and Cotton DWK. Recurrent solitary giant trichoepithelioma located in the perianal area; a case report. British journal of Dermatology; 1988, p.563-566.https://doi.org/10.1111/j.1365-2133.1988.tb02468.x
Brownstein, M. H., & Shapiro, L. (1977). Desmoplastic trichoepithelioma. Cancer, 40(6), 2979–2986. https://doi.org/10.1002/1097-0142(197712)40:6<2979::aid-cncr2820400633>3.0.co;2-8
Thomas, J. A., & Kothare, S. N. (1975). Calcifying epithelioma of Malherbe--a true tumour or a malformation?. Indian journal of cancer, 12(2), 179–186.
Kumar P, Chatura KR, Haravi MR and Chandrashekar HR. Proliferating trichilemmal cyst mimicking squamous cell carcinoma . Indian journal of Dermatology, Verereology and Leprology, 2000; 66: 149-50.
Brownstein H.M and Shapiro L. Trichilemmoma- Analysis of 40 cases. Archives of Dermatology; vol 107; June 1973:866-869.
Reis JP, Tellechea O, Cunha MF and Baptista A.P. Trichilemmal carcinoma : review of 8 cases. Journal of Cutaneous Pathology; 1993; 20: 44-49.
Rulon, D. B., & Helwig, E. B. (1974). Cutaneous sebaceous neoplasms. Cancer, 33(1), 82–102. https://doi.org/10.1002/1097-0142(197401)33:1<82::aid-cncr2820330115>3.0.co;2-4
Shin, J., Jang, Y. H., Kim, S. C., & Kim, Y. C. (2013). Eccrine angiomatous hamartoma: a review of ten cases. Annals of dermatology, 25(2), 208–212. https://doi.org/10.5021/ad.2013.25.2.208
Amin SP and Shah BH. Syringoma- a case report with review of literature. Indian journal of Dermatology, Venereology and Leprology, vol39, No 3;1973:133-137.
Rongioletti, Semino MT and Rebora A. Unilateral multiple plauque like syringoma. British journal of Dermatology 1996; 135:623-625.
Evans HL, Daniel SP, Smith JL and Winkelman RK. Carcinoma arising in eccrine spiradenoma. Cancer 43, 1979: 1881-1884.
Ishimura E, Iwamoto H, Kobashi Y, Yambe H and Ichijima K. Malignant chondroid syringoma. Cancer 52; 1983: 1966-1973.
Stephen MAJ, Rosten MC, Jack MAJ. Syringocystadenoma papilliferum in an unusual location. Arch Dermatol, vol 112, June 1976:pp1274-1281.
Nair SP. A clinicopathological study of skin appendageal tumours. Indian J of Dermatol Venerol Leprol 200874:108-550.